The aim of the present study is to assess the correlation between chronic apical periodontitis and oxidative stress. In fact, chronic apical periodontitis is reactive oral disease and it may cause an imbalance between production and elimination of Reactive Chemical Species (RCS), with a greater risk for onset of paraphysiological and pathological conditions, such as cardiovascular diseases.
MATERIALS AND METHODS
A randomized group of 103 patients between 30 and 68 years of age, presenting with chronic apical periodontitis, was recruited. We assessed the oxidative balance by measuring the oxidant status by d-ROMs Test and the antioxidant status by BAP Test, before endodontic treatment and 30 and 60 days after. Patients were excluded from this study if there was no healing of chronic periodontitis.
On recruitment, patients affected by chronic apical periodontitis presented with higher d-ROMs Test values than the average values of healthy subjects. These values decreased by 28 ± 9% 30 days after endodontic treatment and by 35 ± 10% at 60 days.
DISCUSSION AND CONCLUSIONS
We observed a positive association between oxidative stress and chronic apical periodontitis. We can conclude that the presence of chronic apical periodontitis increases the risk of diseases related to an altered oxidative balance, due to the higher levels of oxidative stress.
The present study also revealed that after treatment of chronic apical periodontitis, the levels of oxidative stress tend to reduce and return to normal after 60 days.
The treatment of these lesions of endodontic origin brings the levels of oxidative stress back to normal, and reduces the risk for onset of diseases related to a condition of oxidative stress.
Congresso Nazionale dei Docenti di Discipline Odontostomatologiche e Chirurgia Maxillo Facciale
Firenze – Siena, 14-16 Aprile 2011
Università degli Studi di Bari Dipartimento di Odontostomatologia e Chirurgia
Direttore: Prof.ssa D. DE VITO
Calabrodental S.r.l. Unità Operativa di Chirurgia Maxillo-Facciale Regione Calabria – Crotone Dir. San: Dott. M. W. Marrelli
F. Inchingolo, F. Schinco* G. Dipalma, M. Serafini, S. Di Teodoro, A. M. Inchingolo, M. De Carolis, M. Marrelli, A. Palladino, A. D. Inchingolo
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