PRP (Platelet Rich Plasma) is a reservoir of growth factors (PDGF,TGF-β,IGF-1,FGF,EGF), which can stimulate angiogenesis, macrophage chemotaxis, fibroblast proliferation and collagen synthesis.
The aim of the present study is to demonstrate the short-term and long-term effectiveness of PRP, in association with filling biomaterials, for bone regeneration of atrophic areas in implantology.
MATERIALS AND METHODS
We present the case of a 40-year-old female patient with a fixed prosthesis. In one surgery, we avulsed tooth 15, performed Summer’s crestal sinus lift by placing PRP-imbibed fibrin sponges and then placed 2 implants; PRP was obtained by sampling autologous blood in sterile test tubes without anticoagulant and by centrifugation.
Postsurgical orthopantomography (OPT) showed an hyper-transparent sinus (empty), indicating the complete absence of bone grafts and only the presence of PRP-imbibed fibrin sponges; OPT and CT scan performed 6 months after surgery revealed a radiographic integration and an increased density of the perimplant bone.
DISCUSSION AND CONCLUSIONS
PRP, being rich in growth factors, associated with fibrin sponges which substantially act as a scaffold, has allowed to achieve a satisfying neo-apposition and bone regeneration, as proved by long-term radiological examinations.
The combined use of PRP, associated with filling biomaterials, is certainly a very interesting technique, which deserves long-term clinical investigations and prospective, experimental studies on a statistically-significant number of patients, with strict and well-defined inclusion criteria and without statistic bias.
Congresso Nazionale dei Docenti di Discipline Odontostomatologiche e Chirurgia Maxillo Facciale
Firenze – Siena, 14-16 Aprile 2011
Università degli Studi di Bari Dipartimento di Odontostomatologia e Chirurgia
Direttore: Prof.ssa D. DE VITO
Calabrodental S.r.l. Unità Operativa di Chirurgia Maxillo-Facciale Regione Calabria – Crotone Dir. San: Dott. M. W. Marrelli
F. Inchingolo, F. Carbotti, G. Dipalma, M. Serafini, M. Marrelli, A.M. Inchingolo, S. di Teodoro, A. Palladino, M. De Carolis, A.D. Inchingolo, M. Tatullo
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